Effect of cGMP on voltage-gated potassium channel in pulmonary artery smooth muscle cells from rats exposed to chronic hypoxia
- VernacularTitle:cGMP对慢性低氧大鼠肺动脉平滑肌细胞膜电压门控钾通道的作用
- Author:
Yongchang ZHANG
;
Wang NI
;
Guohua ZHEN
;
Zhenxiang ZHANG
;
Yongjian XU
- Publication Type:Journal Article
- Keywords:
Guanosine cyclic monophosphate;
Anoxia;
Pulmonary artery;
Potassium channels
- From:
Chinese Journal of Pathophysiology
2000;0(08):-
- CountryChina
- Language:Chinese
-
Abstract:
0.05]. CONCLUSIONS: The currents of voltage-gated potassium channel was inhibited by chronic hypoxic. The inhibitory effect of cGMP on currents of voltage-gated potassium channel in PASMCs from both normal and chronic hypoxic rats may be probably through the phosphorylation of voltage-gated potassium channel.
