Influence of bifidobacterium on NF-?B and I ?B? in experimental large bowel carcinoma
- VernacularTitle:双歧杆菌对实验性大肠癌NF-?B和I?B?的影响
- Author:
Lisheng WANG
;
Huiming ZHU
;
Lingjia PAN
;
Xun HUANG
;
Weixiang LUO
;
Xiaodong MA
;
Yali ZHUANG
;
Dianyua ZHOU
- Publication Type:Journal Article
- Keywords:
Bifidobacterium;
Intestinal neoplasms;
NF-kappa B
- From:
Chinese Journal of Pathophysiology
2000;0(08):-
- CountryChina
- Language:Chinese
-
Abstract:
AIM: To explore the antitumor mechanisms of bifidobacteria adolescence in vivo. METHODS: The activity of NF-?B and its inhibiting protein I ?B? of large bowel carcinoma tissues was detected by using laser scanning confocal microscope and immunohistochemistry. RESULTS: The positive cell density of NF-?B of large bowel carcinoma transplantation tumors in bifidobacterium injection group was markedly lower than that in tumor control group( P