Haemodynamic changes in high altitude pulmonary edema and effects of oxygen breathing
- VernacularTitle:高原肺水肿患者血流动力学变化及对吸氧反应的测定
- Author:
Xinbing MU
;
Suzhi LI
;
Yuqi GAO
;
Fuyu LIU
;
Ganglin YE
;
Hongya TANG
;
Dan ZHU
;
Xiaobo ZHOU
;
Guangli CHEN
- Publication Type:Journal Article
- Keywords:
High altitude pulmonary edema;
Hemodynamics;
Hypertension, pulmonary
- From:
Chinese Journal of Pathophysiology
2000;0(08):-
- CountryChina
- Language:Chinese
-
Abstract:
AIM: To explore the pathogenic mechanism of high altitude pulmonary edema(HAPE). METHODS: Haemodynamic changes and effects of 100 percent oxygen breathing were measured by Swan-Ganz thermistor catheters, high altitude healthy volunteers were served as controls. RESULTS: The important features of haemodynamic changes in HAPE: (1)Pulmonary arterial pressure was raised; (2)Pulmonary arterial resistance and cardiac output were raised; (3)Pulmonary artery wedge pressures and right atrial pressure were normal; (4)Pulmonary arterial pressure and resistance were induced by oxygen breathing. CONCLUSIONS: The normal pulmonary artery wedge pressures with a high cardiac output indicated that HAPE was recognized as a form of noncardiogenic pulmonary edema. The pulmonary hypertension may play an important role in the development of HAPE.
