Mast cell tryptase and asthma
- VernacularTitle:肥大细胞类胰蛋白酶与支气管哮喘
- Author:
Qingxia NIU
;
Shaoheng HE
- Publication Type:Journal Article
- Keywords:
Asthma;
Tryptase;
Serine proteinases;
Mast cells
- From:
Chinese Journal of Pathophysiology
2000;0(08):-
- CountryChina
- Language:Chinese
-
Abstract:
As an important mediator of allergic inflammation, mast cell tryptase is involved in the induction of hypersensitivity, infiltration of inflammatory cells and tissue remodeling in respiratory tract. The effects of tryptase inhibitors on the actions of tryptase show further the potential of tryptase in the pathogenesis of asthma and its inhibitors in the treatment of asthma.