Matrix metalloproteinase-9 and inflammatory reaction
- VernacularTitle:基质金属蛋白酶-9与炎症反应研究进展
- Author:
Ying GAO
;
Dingfang CAI
- Publication Type:Journal Article
- Keywords:
Matrix metalloproteinases;
Inflammation;
Signal transduction
- From:
Chinese Journal of Pathophysiology
2000;0(08):-
- CountryChina
- Language:Chinese
-
Abstract:
MMP-9 is one of the family of matrix metalloproteinases, which degrades extracellular matrix. MMP-9 is induced by many inflammatory factors, including IL-1?,IL-8 and TNF-?. Meanwhile, MMP-9 potentiates inflammatory factors by aminoterminal processing. The signal transduction by which inflammatory factors induce MMP-9 is also an important part in recent research. This review will give a summary in all these fields.
