Clinical significance of CK19 and CD44 expression in peripheral blood of patients with breast cancer
- VernacularTitle:乳腺癌微转移的CK19和CD44表达研究
- Author:
Guangming XING
;
Qing LU
;
Xiaowei HOU
;
Guiping ZHANG
;
Bingan FENG
- Publication Type:Journal Article
- Keywords:
Breast neoplasms;
Metastasis;
Keratin;
Antigens,CD44
- From:
Chinese Journal of General Surgery
2001;0(08):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the expression of CK19mRNA and CD44mRNA in peripheral blood of patients with breast cancer for forecasting micrometastasis. Methods Expression of CK19 and CD44 were detected in 107 patients by RT-PCR method. Results CK19 and CD44 were positive in 31.8%(34/107) and 32.7%(35/107) of patients with breast cancer 24 hours before surgery respectively,which were statistically different from that of 12 days postoperatively and that of normal controls (all P
