Study on Mechanism of Action of Compound Huanggan Granules on the Kidney
- VernacularTitle:复方黄甘颗粒对肾脏的作用机理研究
- Author:
Lianbing HOU
;
Xixiao YANG
- Publication Type:Journal Article
- Keywords:
compound Huanggan granule;
mechanism of action;
renal blood flow;
diu resis
- From:
China Pharmacy
2001;0(08):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To research the mechanism of action of compound Huanggan gr anules(FHG) METHODS:To observe the effect of FHG on the renal blood flow and glomerular filtration rate,and its mechanism of diuresis by means of isotopic tracer,electromagnetic flowmeter and ureter catheterization RESULTS:FHG could significantly increase the renal blood flow and glomerular filtration rate,and enhance the diuresis CONCLUSION:Its diuresis is based on the increase of rena l blood flow and glomerular filtration rate,which results in the decrease of ne phrotoxic substances such as blood urea nitrogen and serum creatinine