Preparation of FLX-TNZ Hollow Effervescent Suppository
- VernacularTitle:氟替中空泡腾栓的研制
- Author:
Lei ZHANG
;
Xin LI
;
Zhonghua LI
;
Yi LIANG
;
Yongjiang CHEN
- Publication Type:Journal Article
- Keywords:
fleroxacin;
tinidazole;
hollow effervescent suppository;
preparation
- From:
China Pharmacy
2001;0(08):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To establish the preparation technic and method of qualit y control of fleroxacin-tinidazole(FLX-TNZ)hollow effervescent suppository METH ODS:36-type semi-synthetic aliphatic ester was used as base material and doub le-wavelength UV-spectrophotometry was adopted for determination of the conten ts of fleroxacin and tinidazole RESULTS:The average recovery rates(n=5)of fler oxacin and tinidazole were 99 72% and 99 08%,while RSDs were 0 95% and 1 02% respectively CONCLUSION:This method has a sound design and feasible tec hnnology
