Protective Effect of KangAiZengXiao Decoction on Immunological Deficit Rats With Implanted Tumor
- VernacularTitle:抗癌增效汤对荷瘤大鼠免疫功能的保护作用
- Author:
Yongli TIAN
;
Jiabang LI
;
Donghua YANG
- Publication Type:Journal Article
- Keywords:
KangAiZengXiao decoction;
Antitumor;
Natural killer (NK) cell;
Transformation efficiency of lymphocyte
- From:
Journal of Chinese Physician
2001;0(08):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the effect mechanism of anticancer synergic (KangAiZengXiao,KAZX) decoction on gastric cancer in immunologic deficit rats with implanted tumor. Methods Forty rats were divided into normal control group(n=10), model group(n=15) and KAZX treating group(n=15). Model group and KAZX group were subcutaneously injected axillary the left upper limb with 0 5ml gastri cancer cells,MGC-803 cell(1?10 7/ml) after irradiated by 60 Co(dose:10Gy). Then the three groups were treated with KAZX decoction or distilled water every day, respectively. After three weeks, the rats were sacrificed,and blood WBC, the weight of spleen, activity of NK cell and transformation efficiency of lymphocyte were also detected.Results The rate of loaded tumor in KAZX group was significantly lower than in model group(20% vs 66 7%,P
