Progress in signal transduction of erythropoietin
- VernacularTitle:红细胞生成素的信号转导研究进展
- Author:
Yulong XIAO
;
Zhenyan ZHAI
;
Weijie YUAN
- Publication Type:Journal Article
- Keywords:
Erythropoietin;
Signal transduction;
Receptors, erythropoietin
- From:
Chinese Journal of Pathophysiology
2000;0(07):-
- CountryChina
- Language:Chinese
-
Abstract:
Erythropoietin is a critical growth factor in development of erythrocyte. After binding to its receptor, eryhropoietin produces biological action through consequent activation of intracellular signal transduction systems, including JAK2-STAT5, sos-Ras-MAPK, IRS-2- PI 3-K + and Ca 2+ channel.
