Apoptosis and its modulation in hepatic ischemia and reperfusion injury
- VernacularTitle:肝脏缺血再灌注损伤与细胞凋亡
- Author:
Yi MA
;
Xiaoshun HE
;
Guihua CHEN
- Publication Type:Journal Article
- Keywords:
Apoptosis;
Reperfusion injury;
Genes;
Liver
- From:
Chinese Journal of Pathophysiology
2000;0(07):-
- CountryChina
- Language:Chinese
-
Abstract:
Hepatic ischemia/reperfusion injury (HIRI) exists in lots of process of clinical pathology and operation. Apoptosis is an active process controlled by some gene and factors such as Fas/FasL, Caspases and Bcl-2 families. More and more studies suggest that HIRI is associated with apoptosis. This article summarized the mechanisms and gene modulation of apoptosis during HIRI and the significance of suppressing apoptosis in preventing HIRI.
