Study on the Tumor Targeting of RGD-PEG-liposomes
- VernacularTitle:RGD多肽结合型长循环脂质体的肿瘤靶向性研究
- Author:
Zhanshan LI
;
Jiping ZHOU
;
Lili WANG
- Publication Type:Journal Article
- Keywords:
RGD-PEG-liposome;
tumor targeting
- From:
China Pharmacy
2001;0(07):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To study the tumor targeting of RGD-PEG-liposomes METHODS:RGD-PEG-liposome was prepared by reverse phase evaporation method and combination with GRGDS peptide Tumor targeting was studied in Colon 26 tumor bearing mice RESULTS:RGD-PEG-liposomes showed good tumor targeting effect on colon 26 tumor bearing mice CONCLUSION:RGD containing polypeptide conjugated,long-cyclic lipsome may become a new-type,receptor-mediated targeting agent
