Study on the Preparation and Quality Control of Indapamide Capsules
- VernacularTitle:吲达帕胺胶囊的研制与质量控制
- Author:
Lequn SU
;
Shujuan SUN
;
Yan MENG
;
Hongjian LI
- Publication Type:Journal Article
- Keywords:
indapamide capsule;
UV-spectrophotometry;
HPLC;
quality control
- From:
China Pharmacy
2001;0(07):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To prepare indapamide capsules and study the quality control methods METHODS:The content of indapamide in capsules was determined by UV-spectrophotometry The other ingredients were determined by HPLC RES_ULTS:The calibration curve was linear within the concentration range of 3 7～11 1?g/ml(r=0 9 997);the recovery of indapamide was 99 50%,RSD=0 43% The RSDs of indapamide and other ingredients were 0 43% and 0 1% respectively The relative percentage contents of 3 batches of sample were 99 07%,99 34%,99 58% respectively The uniformity A+1 80S of contents of indapamide in all samples detected was
