Imbalance of Th1/Th2 Cytokines Produced by PBMC in Patients with Pregnancy Induced Hypertension
- VernacularTitle:妊娠高血压综合征患者外周血单个核细胞产生Th1、Th2型细胞因子失衡的研究
- Author:
Jun WEI
;
Tao SHANG
;
Dezhi WANG
- Publication Type:Journal Article
- Keywords:
Pregnancy, complications, cardiovascular;
Hypertension;
Leukocytes, mononuelear;
Cytokines
- From:
Chinese Journal of Perinatal Medicine
2000;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the change of Th1, Th2 cytokine levels in culture supernatants of PBMC in pregnancy induced hypertension (PIH). Methods 43 PIH patients, 15 normal pregnant women, and 15 healthy non-pregnant women were studied randomly. Levels of IL-2?IFN? and IL-4 in culture supernatants of PBMC were detected by ELISA. Results In culture supernatants of PBMC, IL-2 level of normal pregnant women was(140.3? 73.2 )ng/L, decreased significantly in comparation with that of healthy non-pregnant women (259.5?114.4)ng/L, P
