Human Cytomegalovirus Infection Leading to Endothelial Function Disorder and Its Possible Role in Acute Coronary Syndrome Pathogenesis
- VernacularTitle:人巨细胞病毒感染致内皮功能异常在急性冠脉综合征发病中的作用
- Author:
Dingan OUYANG
;
Zhaohui WAMG
- Publication Type:Journal Article
- Keywords:
Coronary heart disease;
ACS;
Human cytomegalovirus;
ET-1;
sICAM-1
- From:
Journal of Chinese Physician
2001;0(07):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the relationship between HCMV infection and endothelial function disorder and its possible role in CHD and acute coronary syndrome (ACS).Method HCMV-DNA, IgM, IgG, ET, sICAM were detected in 59 patients with CHD(CHD group) and 27 patients without CHD(non-CHD group ). The CHD group was divided into acute coronary syndrome group (group A,n=35) and stable symptom group (group B,n=24).Results The positive rate of HCMV-DNA, IgM, IgG was higher in CHD group, especially in group A than that in non-CHD group (P
