Effects and Clinical Significance of Angelica Sinensis Injection on the Functional State of Platelet in Patients With Ulcerative Colitis
- VernacularTitle:当归注射液对溃疡性结肠炎患者血小板功能状态的影响及其意义
- Author:
Shaoping LIU
;
Weiguo DONG
;
Shaochun LIU
- Publication Type:Journal Article
- Keywords:
Angelica Sinensis injection;
Ulcerative colitis;
Platelet activation;
vWF:Ag
- From:
Journal of Chinese Physician
2001;0(07):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the effects of the effective composition of Angelica sinensis injection on the functional state of platelet in patients with ulcerative colitis (UC),and its significance of therapy.Methods In 64 patients with UC and 30 healthy people, a-granule membrane protein (GMP-140), thromboxane B 2(TXB 2), 6-keto-PGF 1a were detected by means of ELISA.Platelet adhesion rate was detected by the platelet adhesion meter, von willebrand faetor related antigen (vWF:Ag) was also detected by the means of monoclonal -ELISA.Results The indexes of platelet activation and vWF:Ag in patients with UC were significanrly higher than those in the control group (P
