Protective Effect of Phellinus Igniarius on CCl 4 -induced Liver Injury in Rats
- VernacularTitle:桑黄对四氯化碳致大鼠肝损伤的保护作用
- Author:
Wanguo ZHANG
;
Jinhong HU
;
Zhen CAI
;
Jin HUANG
- Publication Type:Journal Article
- Keywords:
Phellinus igniarius;
liver injury;
interleukin-4;
interferon-?
- From:
China Pharmacy
1991;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To study the protecting effect of Phellinus igniarius on liver injury.METHODS:Liver injury was induced by carbon tetrachloride in rats.Parameters of serum samples and tissue samples were analyzed to show the effect of Phellinus igniarius on liver injury.RESULTS:Degeneration of hepatocytes was obviously prevented in rats treated with Phellinus igniarius;the liver construction was well maintained.Phellinus igniarius could significantly decrease the serum levels of aminotransferase,active oxygen and IL-4,while increase the serum level of IFN-?and SOD activity in liver tis?sue.CONCLUSION:Phellinus igniarius can protect hepatocytes from injury through anti-lipid peroxidation and regulating inflammatory factors.
