Change of serum vascular endothelial growth factor level in patients with bladder transitional cell carcinoma
- VernacularTitle:膀胱移行细胞癌患者血液中血管内皮生长因子的研究
- Author:
Zhenghui GUO
;
Hua MEI
;
Jian HUANG
;
Yousheng YAO
;
Kewei XU
;
Chun JIANG
- Publication Type:Journal Article
- Keywords:
Bladder neoplasms;
Vascular endothelial growth factors;
Blood;
Pirarubicin;
Operation
- From:
Chinese Journal of Pathophysiology
1986;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
AIM: To investigate serum vascular endothelial growth factor (VEGF) level in patients with bladder transitional cell carcinoma(BTCC) and its clinical significance. METHODS: ELISA method was used to examine the serum VEGF level in 42 cases of bladder transitional cell carcinoma and in 10 cases of normal people as control. The change of VEGF in blood of the pre-operation and post-operation patients with BTCC was also compared. RESULTS: The VEGF level in blood of the patients was higher than that of the normal people, in spite of pre-operation, post-chemotherapy, and post-operation, but VEGF level decreased obviously after chemotherapy or operation. In addition, the plasma VEGF level was related to the grade and invasion of tumor. CONCLUSION: Detecting serum VEGF level can help us to assess the change of tumor and therapeutic effect.
