Study on the in Vitro Sensitivity of Lung Cancer Tissue to Commonly-used Antineoplastics
- VernacularTitle:常用抗癌药物对肺癌的体外敏感性研究
- Author:
Yi SONG
;
Xiaoou PAN
;
Shulan YUAN
;
Yun LIAO
- Publication Type:Journal Article
- Keywords:
lung cancer;
sensitivity of drug;
MTT assay
- From:
China Pharmacy
1991;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To study the in vitro sensitivity of lung cancer tissue to commonly-used antineoplas?tics.METHODS:The sensitivity of45fresh samples of human lung cancer to15commonly-used antineoplastics was deter?mined by MTT method.RESULTS:Lung cancer was more sensitive to CBP,VM26,THP,DDP,BLM,MTX and HCPT.However,there was individual difference in sensitivity to the same drug.CONCLUSION:The sensitivity assay of chemotherapeutic agents could provide important information for selection of the agents and MTT assay is a rapid and simple method for detecting the sensitivity of antineoplastics.
