Prevention and treatment of complications after endoscopic esophageal mucosal resection for early esophageal cancer and precancerous lesion
- VernacularTitle:内镜下食管黏膜切除并发症的预防和治疗
- Author:
Guiqi WANG
;
Wenqiang WEI
;
Changqing HAO
- Publication Type:Journal Article
- Keywords:
Esophageal neoplasms;
Mucosal resection;
Postoperative complication
- From:
Chinese Journal of Digestive Endoscopy
2001;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the treatment outcome of endoscopic esophageal mucosal resection (EMR) and alleviate or prevent the complication of EMR. Methods We explore a strategy of endoscopic esophageal mucosal resection to treat early esophageal cancer and severe dysplasia . Endoscopic esophageal mucosal resection was performed with transparent-cap technique, resdiual lesions were treated by Argon Plasma Cocagulation( APC). All patients have been followed up by endoscopic examinations at one month, 4 months, and 12 months after therapy. Results Seventy one cases (88 lesions) were treated by endoscopic esophageal mucosal resection with transparent-cap method. Average doses of saline-epinephrine 18 ml is injected submucosally to each lesion. The resected specimens were on average(21.8 ?1.0)mm ? (18.2?1. 0)mm in size. Five cases have bleeding after mucosectomy, bleeding were managed and controlled by compression , local injection of saline-epinephrin, and APC. Perforation never occurred. Four cases have stenosis after mucosal resection, in three of them the resected area was more than 3/4 esophageal circumference, then it was dilated with water ballon dilater at one month, two months and three months after mucosal resection, all cases were cured. Conclusions Endoscopic esophageal mucosal resection is a safe, simple, minimally invasive and effective procedure with few complication in treating early esophageal cancer and precan-cerous lesion.