Effect of Budesonide on the IL-16 in Sputum from Patients With Asthma
- VernacularTitle:吸入性激素对哮喘患者痰中IL-16影响
- Author:
Zhiying LI
;
Tinyan LIN
;
Feng WU
- Publication Type:Journal Article
- Keywords:
Interleukins;
Steroid;
Hormone;
Sputum;
Asthma
- From:
Journal of Chinese Physician
2001;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To inestigate the effect of inhaled steroid hormone on the IL-16 in sputum from paitents with asthma, and to explore the mechanism of anti-inflammation of steroid. Method Budesonid inhalant were administered(400?g twice a day) persistent 4 weeks for 12 subjects with mild to moderate asthma, The percentage of eosinophils and IL-16 in induced sputum were determined in every subject .Result After the course , the concentration of IL-16 in sputum was (41 5?5 2)ng/L, significantly lower than that before the therapy which was (58 2?7 2)ng/L,P
