Clinical Efficacy and Safety of Adapalene0.1%Gel with Individualized Treatment Regimen for Acne Vulgaris
- VernacularTitle:阿达帕林凝胶个体化治疗寻常痤疮的临床研究
- Author:
Zhuyun XUE
;
Chengquan DU
;
Guohong LIU
;
Zhigang BI
;
Songhua YAN
;
Dan LUO
- Publication Type:Journal Article
- Keywords:
Acne vulgaris;
Adapalene
- From:
Chinese Journal of Dermatology
1995;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the clinical efficacy and safety of adapalene0.1%gel with individ-ualized treatment regimen for acne vulgaris(ITRAV).Methods Eighty-one patients with acne vulgaris of mild to moderate severity were treated with adapalene0.1%gel topically1to3times daily for6to8weeks according to the severity of the disease.Clinical responses were recorded and photographed weekly in30pa-tients randomly selected from the81patients,and treatment regimens were adjusted accordingly.Results It was shown that cure rates were44.4%and73.4%,in81recruited cases and30selected cases,respectively.Seborrhea decreased remarkably(83.3%)in the treatment.Side effects took place in39.5%of patients with-out interruption of the treatment.Conclusions ITRAV with adapalene0.1%gel has been proved to have an excellent response.Reasonably increasing the daily dosage could improve the cure rates.The cutaneous tolera-bility of the drug was generally good.Seborrhea could be reduced considerably during the treatment
