Inhibitory Effects of Extracted Components from Chinese Medicinal Herbs on Tyrosinase
- VernacularTitle:14种中药提取成分对酪氨酸酶活性的抑制作用
- Author:
Liuyi YANG
;
Yu CAO
;
Yujia WEI
;
Dawei LEI
- Publication Type:Journal Article
- Keywords:
Monophenol monooxygenase;
Eugenol;
Curcumin;
Gallic acid;
Ecdysone;
Drugs,Chi-nese herbal
- From:
Chinese Journal of Dermatology
1995;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To develop an in vitro method to determine the effects of drugs on tyrosinase(TYR)activity and screen the inhibitory effects on TYR of14extracted components of Chinese medicinal herbs.Methods The activity of TYR was detected by revised Matsuda's method.Effects of14extracted com-ponents on tyrosinase system were observed in vitro.Results Ten of the14components showed dose-depen-dent down-regulation of tyrosinase activity and melanogenesis.The inhibitory activities of eugenol,curcumin and gallic acid were significantly higher than those of arbutin(P
