Effects of bFGF and insulin on proliferation of mice cartilage tissue cells
- VernacularTitle:成纤维细胞生长因子和胰岛素对小鼠软骨细胞增殖的影响
- Author:
Yunxia CUI
;
Jingfang DI
;
Yaoying ZENG
;
Shan ZENG
;
Zhen FENG
;
Yifei WANG
- Publication Type:Journal Article
- Keywords:
Cartilage;
Fibroblast growth factors, basic;
Insulin;
Mice
- From:
Chinese Journal of Pathophysiology
1986;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
AIM: To explore the effects of basic fibroblast growth factor ( bFGF) and insulin on the cell proliferation and differentiation in primary cartilage cells. METHODS: After induction with different concentrations of bFGF and insulin, cell proliferation was measured with WST-1 method and fluoroscope methods. RESULTS: bFGF and insulin exerted their related action on primary cartilage cells in 0.4% fatal bovine serum at different concentrations. 25 ?g/L bFGF and 5 mg/L insulin promoted cell proliferation significantly. CONCLUSION: bFGF and insulin prolong the survival time and promote cell proliferation in primary cartilage cells.
