Recent advances in molecular mechanisms of cerebral ischemic injury
- VernacularTitle:脑缺血损伤的分子机制研究进展
- Author:
Jianyun YAN
;
Weikang WU
- Publication Type:Journal Article
- Keywords:
Brain ischemia;
Excitatory amino acids;
Free radicals;
Caspases;
Calcium;
Cytokines
- From:
Chinese Journal of Pathophysiology
1986;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Acomplexcascadeofmoleculareventsisconsiderdtobeinitiatedfollowingcerebralis chemia ,whichincludereleaseofexcitatoryaminoacid ,calciumdyshomeostasis ,freeradicalinjury ,increased cytokines,caspaseactivationandalteredgeneexpression .Thisreviewprovidesanoverviewofmolecular mechanismsinvolvedinpostischemicneuronaldeathandanalysesthepotentialfortherapeuticintervention .
