A study on the B7-CD28 costimulatory pathway in breast cancer patients
- VernacularTitle:乳腺癌患者B7-CD28共刺激通路的研究
- Author:
Ping FAN
;
Shui WANG
;
Xiao LIU
- Publication Type:Journal Article
- Keywords:
Breast neoplasms;
Costimulatory pathway;
B7 molecules;
CD28 molecules
- From:
Chinese Journal of General Surgery
1993;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate costimulatory pathway of breast cancer patients, we examined peripheral CD28 positive T lymphocytes and B7 molecules expression on the primary breast cancer cells in patients with breast cancer. MethodsFlow cytometry was used to analyze CD28 and B7 molecules expressed on T lymphocytes and primary breast cancer cells respectively. Results CD28 positive T lymphocytes in breast cancer patients was lower than that in control group (t=2.879,P