Study on the Preparation of PEG-SOD Enteric-coated Capsuls
- VernacularTitle:聚乙二醇6000修饰超氧化物歧化酶肠溶胶囊的研制
- Author:
Bo JI
;
Shujin ZHAO
- Publication Type:Journal Article
- Keywords:
PEG;
SOD;
enteric coated capsule;
fomula;
preparation technic;
quality control
- From:
China Pharmacy
1991;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To study the method of preparing PEG-SOD enteric-coated capsuls and quality standard.ME_ THODS:Orthogonal design was used to select the optimal conditions for preparing PEG-SOD enteric-coated capsuls and the relevant quality standard of PEG-SOD enteric-coated capsuls was established according to the China Pharmacopoeia(2000). RESULTS:The optimal conditions were as follows:the content of PEG-SOD per capsule was40000IU;the weight ratio of stabilizer lactose was2.5%;filler was carboxymethyl starch;drying process was at60℃for20min.The preparation was ac?corded with the relevant quality standard.CONCLUSION:The technic of preparation is feasible,the method of quality control is reliable and the quality of preparation is stable.
