Preparation of Anhydrous Hand-cleaning Agents
- VernacularTitle:无水洁手剂的研制
- Author:
Yongshi HU
;
Xianhai JIANG
;
Cunhe LIN
;
Geqiong ZHANG
;
Qingyun DU
- Publication Type:Journal Article
- Keywords:
anhydrous hand-cleaning agent;
PVA;
PVP-I;
iodine value
- From:
China Pharmacy
1991;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To prepare anhydrous iodine-containing or iodine-free hand-cleaning agents for use at field or water-deficient area.METHODS:An adhesive paste was made with PVA as vehicle and PVP-I as disinfector.Iodine value was taken as parameter of quality control.The adhesive-eliminating test was carried out on Escherichia coli and HBV elimi?nating and skin irritation tests were performed in rabbits.RESULTS:This preparation could eliminate bacteria by its adhesive action and had considerable disinfective action because of the ingredient iodine,however it could not eliminate HBV.No irrita?tion to skin was found.CONCLUSION:The preparation can effectively remove the dust,bacteria and viruses from the hands and is suitable for cleaning hands in conditions of wartime,training and water-deficient area.