Determination of Hydroquinone in Compound Hydroquinone Cream by HPLC
- VernacularTitle:高效液相色谱法测定复方氢醌霜中氢醌的含量
- Author:
Ting ZHANG
;
Xinzhong LI
- Publication Type:Journal Article
- Keywords:
HPLC;
hydroquinone;
compound hydroquinone cream
- From:
China Pharmacy
1991;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To establish a HPLC method for the determination of hydroquinone in compound hydroquinone cream.METHODS:The assay was conducted on a Kromasil-C 18 column with methanol-water(30∶70)as mobile phase and the detection wavelength was293nm.RESULTS:The linear concentration range of hydroquinone was2.5~60?g/ml with the recovery of99.9%(RSD=0.73%).CONCLUSION:The method may be used for the determination of hydroquinone in cream.