Expression of Vascular Endothelial Growth Factor in Patients With Acute Myocardial Infarction
- VernacularTitle:急性心肌梗塞患者血管内皮生长因子的动态表达
- Author:
Yi ZHANG
;
Shushan QI
;
Shenghua ZHOU
- Publication Type:Journal Article
- Keywords:
Vascular endothelial growth factor;
Acute myocardial infarction;
Creatine kinase
- From:
Journal of Chinese Physician
2001;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the clinical significance of vascular endothelial growth factor (VEGF) levels in the serum of patients with acute myocardial infarction (AMI),and also to explore the relationship between VEGF and creatine kinase (CK) levels in AMI.Methods 25 patients with AMI and 12 controls were used for this study. Serum was isolated from peripheral blood on day 1, 5, 10 and15 after the onset of AMI. VEGF levels were measured by enzyme-linked immunosorbant assay (ELISA).Results Serum VEGF levels elevated gradually after the onset of AMI and reached a peak on day 10, which was significantly higher than that of control group (178 9?48 9)pg/ml vs(64 9?16 7)pg/ml,P