Determination of Midecamycin A_1 in Midecamycin Tablets by HPLC
- VernacularTitle:高效液相色谱法测定麦迪霉素片中麦迪霉素A_1的含量
- Author:
Haiyan CHEN
;
Zhi ZHUO
;
Jie ZENG
- Publication Type:Journal Article
- Keywords:
midecamycin tablets;
meleumycin tablets;
midecamycin A1;
HPLC
- From:
China Pharmacy
1991;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To establish a method of determination of midecamycin A1 in midecamycin tablets METHODS:This method used C18 column as stationary phase,0 1mol/L ammonium formate solution-acetonitrile(80∶55) as mobile phase and 232nm as detection wavelength RESULTS:There was a good linear correlation in the range of 0 5～8mg/ml,r=0 9 995,S=5 989C-24 65,RSD=1 4%(n=5) The mean recovery was 99 35% and RSD=1 2%(n=6) CONCLUSION:The method is simple and easy to do and may be adopted for quality control of this drug
