The relation between Helicobacter pylori infection and the amount of interleukin-8 and granulocyte clolny-stimulating factor
- VernacularTitle:幽门螺杆菌感染与白细胞介素-8、粒细胞集落刺激因子含量的关系
- Author:
Feng XU
;
Hua LIU
;
Ying SUN
- Publication Type:Journal Article
- Keywords:
Helicobacter pylori;
Interleukin - 8;
Granulocyte colony-stimulating factor
- From:
Chinese Journal of Digestive Endoscopy
2001;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the relationship between Helicobac ter pylori (Hp) related gastritis and gastric mucosa content of interleukin - 8 (IL-8) and granuloeyte colony-stimulating factor ( G-CSF). Methods ELISA was used to detect the amount of IL-8 and G-CSF in supernate fluid of gastromucosal tissue culture from 60 patients, and to examine the difference between Hp infected and non-Hp infected cases. These 60 cases include normal gastric mucosa (n =20) , chronic gastritis mucosa (n = 14) , gastric ulcer mucosa (n = 13) , duodenal ulcer mucosa ( n = 13 ). Results The amounts of IL-8 and G-CSF in cases with Hp infection were significantly higher than those without infection (P
