Role of natural killer cell in natural protection against HIV-I infection among exposed uninfected IDUs in Vietnam
- Author:
Truong Xuan Lien
- Publication Type:Journal Article
- Keywords:
HIV, natural killer cell
- MeSH:
HIV;
prevention & control;
Killer Cells, Natural
- From:Journal of Preventive Medicine
2004;14(5):5-9
- CountryViet Nam
- Language:Vietnamese
-
Abstract:
The role of natural killer cell in natural protection against HIV-1 infection was studies on 37 injected drug users (IDUs) who had been in high risk of exposure to HIV-1 but remain uninfected (EU) for many years follow-up. A comparison had been conducted between 10 IDUs who underwent seroconversion and 28 unexposed blood donors (controls). The results showed that the lytic activities and cytokines production of natural killer cells were significantly augmented in EU IDUs. This findings supports the role of natural killers cells in contribution to the natural immune response against HIV-1 infection among exposed uninfected IDUs
