Clinical Study on Treatment of Severe Acute Pancreatitis With Somatostatin,Octreotide and Growth Hormone
- VernacularTitle:施他宁、善得定和生长激素治疗重症急性胰腺炎的临床疗效观察
- Author:
Qing ZHANG
;
Mingping LA
;
Jun XU
- Publication Type:Journal Article
- Keywords:
severe acute pancreatitis;
Somatostatin;
growth hormone;
Octreotide
- From:
China Pharmacy
1991;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To evaluate the therapeutic effects of Somatostatin,Octreotide and growth hormone for severe acute pancreatitis(SAP).METHODS:39 patients with SAP were divided into two groups.The treatment group including 21 patients admitted from July,1993 to November,2001 received traditional therapy in combination with Somatostatin,Octreotide or growth hormone;the control group including 18 patients admitted from October,1991 to March,1995 received only traditional therapy.The changes in the APACHE Ⅱ on the first day,third day and seventh day after treatment,the duration of hospital stay,the incidence of complications,curative rate,mortality,the days for serum amylase restoration and the duration of improvement of main symptoms were compared between two groups.RESULTS:Somatostatin,Octreotide and growth hormone could reduce the occurence of complications,decrease the mortality and shorten the duration of hospital stay,days for serum amylase restoration and duration of improvement of main symptoms.CONCLUSION:It is suggested that Somatostatin,Octreotide and growth hormone may be the effective drugs for treating the patients with SAP.
