Study on the Dissolubility of Metformin Hydrochloride Tablets From 14 Pharmaceutical Factories
- VernacularTitle:对14个厂家盐酸二甲双胍片溶出度的考察
- Author:
Jiying YU
;
Min XU
;
Xuguang CHEN
;
Shiming SUN
- Publication Type:Journal Article
- Keywords:
metformin hydrochloride tablet;
dissolubility;
UV-spectrophotometry
- From:
China Pharmacy
1991;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To investigate the dissolubility of commercial metformin hydrochloride tablets from different manufactories.METHODS:The in vitro dissolubility of 14 kinds of commercial metformin hydrochloride tablets was determined by basket method and the dissolution parameters were analyzed with variance analysis method.RESULTS:The in vitro dissolubility of 14 kinds of metformin hydrochloride tablets fitted to the request of ChP2000,but the dissolution parameters were different.CONCLUSION:The statistical results indicate that there are significant differences between products from different factories(P
