Spontaneous Remission of Congenital Leukemia-One Case Report
- VernacularTitle:先天性白血病自然缓解一例报告(附文献回顾)
- Author:
Juan XIAO
;
Danhua WANG
;
Zhenghong LI
- Publication Type:Journal Article
- Keywords:
Leukemia;
Neoplasm regression, spontaneousbjective To study the relative risk(RR) of mortalities of cerebro-cardiovascular diseases(CVD) in Guangzhou workers with hypertension. Method Prospective cohort study was conducted in 78 379 worke
- From:
Chinese Journal of Perinatal Medicine
1998;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To discuss the clinical features and possible mechanisms of congenrtal leuleemia spontaneous remission. Methods By means of literature review, 17 cases with spontaneous remission of congenital leukemia were retrospectively analyzed. Results Among the 17 patients, 8 were persistent remission(47%), 9 had late relapses(53%). Neither initial white cell count nor bone marrow involvement was associated with late relapses. 5 cases(29%) had abnormal karyotype and gene rearrangment,11q23 translocation indicated poor prognosis. Conclusions Conservative treatment can be given unless there was evidence of progressive leukemia. Because of occasional late relapses, long term follow-up was recommended. The detection of karyotype and gene rearrangment was a powerful prognostic tool available.
