Value of Tumor Markers in the Differential Diagnosis of Malignancy-related and Non-malignant Ascites
- VernacularTitle:肿瘤标志物对良恶性腹水鉴别诊断价值的探讨
- Author:
Yongmei DENG
;
Ye SHI
;
Yulun LIU
- Publication Type:Journal Article
- Keywords:
Ascites;
Diagnosis;
Differential diagnosis;
Tumor marker
- From:
Journal of Chinese Physician
2001;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the new way of the differential diagnosis of malignancy-related and non-malignant ascites.Methods 152 patients included 66 cases of liver cirrhosis, 21 cases of tuberculousperitonitis, 38 cases of hepatocellular carcinoma and 27 cases of other malignant tumors with ascites were studied. The levels of tumor markers (AFP, CEA, CA19-9 and CA125) in sera and ascites were measured.Results The diagnostic sensitivity of AFP, CEA, CA19-9 and CA125 in the malignancy-related ascites were 75 0%, 73 8%, 63 6% and 66 7%, respectively. And the specificity were 86 4%, 77 6%, 88 4% and 74 1%, respectively. The level of serum AFP, CEA, CA19-9 and CA125 were remarkably higher in malignancy-related ascites than that in non-malignant ascites(P
