Study on the Risk Factors of Flare in Systemic Lupus Erythematosus
- VernacularTitle:系统性红斑狼疮病情活动相关因素的研究
- Author:
Dongyan HU
;
Ming LI
- Publication Type:Journal Article
- Keywords:
Lupus erythematosus,systemic;
Flare;
Risk factors
- From:
Chinese Journal of Dermatology
1995;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the risk factors of flare in systemic lupus erythematosus(SLE).Methods In this retrospective cohort study132cases of SLE were followed up for1～5years.The risk factors of SLE flare were analyzed by univariate and multivariate logistic regression with computer software,SPSS.Results Of the132patients,82cases had more than one flare,the total number of flares was115.The incidence of flare was0.22per patient-year.The frequency of flares within5years after diagnosis of SLE was higher than that in more than5years.By univariate logistic regression analysis the age younger than40years at the beginning of the study,age of disease onset younger than32years,stress,depression,overwork,pregnancy,suffering from infectious disease,and quick decreasing of prednisone dosage significantly increased the risk of flare(P
