Expression of IFN-?mRNA and IL-10mRNA on Peripheral Blood Mmononuclear Cells of Patients With Pemphigus
- VernacularTitle:天疱疮患者外周血单一核细胞?干扰素、白介素10mRNA表达水平的研究
- Author:
Xiaoqun LUO
;
Yan JIN
;
Feng LI
;
Songli XU
;
Haijun FU
;
Mengwu WENG
- Publication Type:Journal Article
- Keywords:
Pemphigus;
Interferon typeⅡ;
Interleukin-10;
RNA,messenger
- From:
Chinese Journal of Dermatology
1995;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To probe the Th cytokine pattern in pemphigus,so as to clarify the pathogenesis of pemphigus and draw up new therapy.Methods Reverse transcription-polymerase chain reaction(RT-PCR)was used to examine the interferon gamma(IFN-?)and interleukin10(IL-10)mRNA expression on peripheral blood mononuclear cells(PBMCs)of20cases of pemphigus in acute stage,20cases in stable stage,and20normal controls.Results The IFN-?mRNA expression in20cases of pemphigus in acute stage was higher than that of controls(P
