Effect of propofol and fentanyl on perioperative inflammatory changes in children undergoing open heart surgery
- VernacularTitle:异丙酚、芬太尼对小儿心脏手术围术期炎症反应的影响
- Author:
Xin WANG
;
Xiaodong WEI
;
Fang XIA
- Publication Type:Journal Article
- Keywords:
Propofol;
Fentanyl;
Cardiopulmonary bypass;
Child;
Inflammation
- From:
Chinese Journal of Anesthesiology
1995;0(12):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the effect of propofol and fentanyl on inflammatory response to tissue injury in children undergoing open heart surgery with CPB and the possible mechanism. Methods Twenty HYHA class Ⅱ - Ⅲ children with congenital heart disease, aged 10 month-12yr, undergoing elective open heart surgery were randomly divided into two groups: group F in which anesthesia was maintained with high dose fentanyl (50-80?g? kg-1 ) and group FP in which anesthesia was maintained with propofol infusion (20mg?kg-1?h-1 ) and intermittent iv boluses of fentanyl (
