Clinical Analysis of Relationship Between Sjgren′s Syndrome and Other Assoc iated Skin Diseases
- VernacularTitle:干燥综合征伴发其他皮肤病的临床分析
- Author:
Manli YANG
;
Xingshu ZHANG
- Publication Type:Journal Article
- Keywords:
Sjgren′s syndrome;
Skin diseases
- From:
Chinese Journal of Dermatology
1994;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the relationship between Sjgren′s synd rome and associated other skin diseases. Methods Clinical features, laboratory a nd histopathological findings and causes were analyzed retrospectively in 13 cas es of Sjgren′s syndrome. Results Thirteen patients were studied, including 1 male and 12 female, the mean age of onset was 35.3 years old. All 13 cases prese nted features of xerostomia and xerophthalmia. The diagnosis was confirmed by po sitive Schirmer′s test, corneal fluorescein staining, and sialography. The asso ciated other dermatoses were verruca planae, pemphigus, lichen planus, vitiligo, herpes zoster, herpes simplex and systemic lupus erythematosus. All cases were treated with Chinese traditional and western medicines. Twelve cases improved ma rkedly, one eventually died of liver and renal failure and circulation failure. Conclusions The pathogenesis of Sjgren syndrome may be linked to autoimmunity, and immunological aberration has been implicated in most of associated skin dis eases. The intrinsic relationship between Sjgren syndrome and associated other dermatoses needs further investigation.
