Prevalence of Resistant Neisseria gonorrhoeae and Plasmid-mediated Resistant Strains in Guangzhou, 1996-2001
- VernacularTitle:1996-2001年广州地区淋球菌耐药性和质粒介导耐药株流行趋势
- Author:
Jianxing DIAO
;
Heping ZHENG
;
Wenling CAO
;
Xingzhong WU
- Publication Type:Journal Article
- Keywords:
Neisseria gonorrhoeae;
Drug resistance,microbial;
Microbial sensi tivity tests
- From:
Chinese Journal of Dermatology
1994;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the prevalence of resistant Neisseria gon orrhoeae and plasmid-mediated resistant strains in Guangzhou from 1996 to 2001. Methods The resistant N.gonorrhoeae and plasmid-mediated resistant strains to tetracycline (TRNG) were determined using agar dilution method, and penicillinas e-producing N. gonorrhoeae (PPNG) by acidometric method. Results A total of 793 gonococcal isolates were tested from 1996 to 2001. The resistant rate for penic illin increased from 57.2%to 81.8%and PPNG from 2%to 27.2%, respectively, du ring the six years. Resistance to tetracycline remained high and stable over the years, while the rates of TRNG were increased from 1.5%to 27.2%. Conclusions The prevalence of plasmid-mediated resistant strains of N. gonorrhoeae increase s year by year in Guangzhou. These results suggest that the clinical isolates of gonococcal strains in this city are highly resistant to penicillin and tetracyc line.
