Effect of Bidouyan Oral Liquid on Granulocyte-macrophage Colony-stimulating Factor Release and Epithelial Cell Proliferation of Nasal Polyps
- VernacularTitle:鼻窦炎口服液对鼻息肉上皮细胞及粒细胞-巨噬细胞集落刺激因子的影响
- Author:
Yuli ZHANG
;
Hongru ZHANG
;
Zaiwen HAN
;
Qingming LIU
- Publication Type:Journal Article
- Keywords:
nasal polyp;
epithelial cell;
GM-CSF;
Bidouyan oral liquid;
eosinophil
- From:
China Pharmacy
2001;0(12):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To investigate the effect of Bidouyan oral liquid(BOL) on granulocyte-macrophage colony-stimulating factor(GM-CSF) release,ultrastructure changes of eosinophil and epithelial cell proliferation in cultured tissue of nasal polyps METHODS:Nasal polyp tissue was cultured in medium containing different concentrations of BOL The growth of epithelial cells surrounding tissue block and ultrastructure changes of eosinophil in culture tissue were observed The content of GM-CSF in supernate was detected by ELISA RESULTS:In comparison with control,the neogenetic epithelial cells cultured in medium with BOL were fewer in number The contents of GM-CSF were decreased with the increase of the concentrations of BOL with significant differences(P
