Study on the Feasibility of Bacterial Endotoxin Test for Hepatocyte Growth-promoting Factors Injection
- VernacularTitle:促肝细胞生长素注射液细菌内毒素检查可行性研究
- Author:
Peifang SUN
;
Lianxin LI
;
Weidong ZHANG
;
Jianmin WANG
- Publication Type:Journal Article
- Keywords:
hepatocyte growth-promoting factors injection;
bacterial endotoxin;
interference test
- From:
China Pharmacy
2001;0(12):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To study the feasibility of bacterial endotoxin test for hepatocyte growth-promoting factors injection as a substitution for pyrogen test METHODS:According to China Pharmacopoeia(second part,2000),interference test was carried on endotoxin detection of hepatocyte growth-promoting factors injection with limulus lysate test agents produced by two different factories RESULTS:There was no interference with the reaction between bacterial endotoxin and limulus lysate test agent in hepatocyte growth-promoting factors injection in 10-fold dilution CONCLUSION:It is feasible to use the gelatine method in bacterial endotoxin test
