Relationship between Impaired Glucose Tolerance Test and Insulin Resistance During Pregnancy
- VernacularTitle:妊娠期葡萄糖耐量受损与胰岛素抵抗
- Author:
Xianming XU
;
Yi XIE
;
Mingli JIANG
- Publication Type:Journal Article
- Keywords:
Glucose intolerance;
Insulin resistance;
Glucose tolerance test
- From:
Chinese Journal of Perinatal Medicine
2000;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the relationship between impaired glucose test and insulin resistance in pregnancy. Methods Ninety-three pregnant women who had one abnormal result among 4 of oral glucose tolerance test (OGTT) and 179 pregnant women who had normal results of OGTT from 11 hospitals of Shanghai during May 1999 to Aug 1999 were included. Insulin release test were performed at the same time. Insulin sensitive index (ISI), islet secretive function index (IFI) were calculated. Area under sugar curve (SAUC)?area under insulin curve (IAUC)?ISI? IFI?fast plasma sugar(PGO) and fast plasma insulin (INO) were compared between two groups. Results PGO, INO, SAUC, IAUC and ISI of the IGT group and control group were(5.1?1.0)mmol/L vs(4.3?0.4)mmol/L?(142?77) pmol/L vs (114?40)pmol/L?(1186?437) pmol/L vs (1058?407)pmol/L?(23?4) mmol/L vs (18?3)mmol/L and 30?20 vs 22?24 respectively, the differences were significant(P0.05). Conclusions Insulin resistance is one of the causes of impaired glucose test in pregnancy.
