Changes of Interleukin-18 and Endothelin-1 in the Patients of Pregnancy Induced Hypertension Syndrome
- VernacularTitle:妊娠高血压综合征患者白细胞介素18和内皮素1的变化研究
- Author:
Chun WANG
;
Tao SHANG
;
Wenjing HOU
- Publication Type:Journal Article
- Keywords:
Pregnancy complications,cardiovascular;
Hypertension;
vascular;
Interleaukin-18;
Endothelin-1
- From:
Chinese Journal of Perinatal Medicine
2000;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the change of interleakin-18 (IL-18) in patients of pregnancy induced hypertension syndrome(PIH) and its correlation with endothelint-1 (ET-1). Methods Serum levels of IL-18 and plasma levels of ET-1 in 47 PIH patients and 30 normal pregnancy women were measured with ELISA and RSA respectively. Results (1)Serum IL-18 of PIH group (M=43.76 ng/L) was significantly higher than that of normal pregnancy group (M=37.975 ng/L) , H=42.845,P