Clinical research on the relationship among plasma endothelin, calcitionin gene-related peptide and chronic atrophic gastritis
- VernacularTitle:血浆内皮素和降钙素基因相关肽与慢性萎缩性胃炎相关性研究
- Author:
Chaoyuan CHEN
;
Yan WANG
- Publication Type:Journal Article
- Keywords:
Chronic atrophic gastritis;
Endothelin;
Calcitonin gene-related peptide
- From:
Chinese Journal of Digestive Endoscopy
1996;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the relationship among the plasma ET,CGRP and chronic atroph-ic gastritis (CAG). Methods One hundred and eighteen cases with GAG, 30 cases with chronic superficial gastritis( CSG) ;30 cases healthy individuals served as control group. The levels of plasma ET,CGRP were measured by radioimmunoassay. Results (1) ET levels were significantly higher in GAG than in CSG and control (P 0. 05) . (2) The levels of plasma ET is statistically different among mild, moderate and severe CAG(P 0.05). (3)The levels of plasma ET were negatively correlated with the levels of plasma CGRP (r = -0. 214,P =0.02). Conclusion It is suggested that ET and CGRP were possibly involved in the pathogenesis of CAG, and their variations in concentrations were related with the extent of CAG.
