Effect of Epidural Anesthesia With 0.375% Ropivacaine on Hemodynamics in Breast Cancer Radical Operation
- VernacularTitle:0.375%罗哌卡因上胸部硬膜外阻滞行乳癌根治术对循环功能的影响
- Author:
Xiaobin WANG
;
Xianlin TAN
;
Qiang QU
- Publication Type:Journal Article
- Keywords:
Ropivacaine;
Bupivacaine;
Epidural anesthesia;
Breast cancer radical operation
- From:
Journal of Chinese Physician
2000;0(12):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the changes of hemodynamics during 0 375% ropivacaine epidural anesthesia period,and 0 375% bupivacaine as control in patients have undergoing breast cancer radical operation.Methods Sixty-one patients were randomly designed to receive 0 375% ropivacaine(groupⅠ,n=30)or 0 375% bupivacain(groupⅡ,n=31)epidural anesthesia respectively during breast cancer radical operation.BP,HR and SpO 2 were assessed at 5min,10min,15min and 20min after first full doses.Results The changes of BP,HR and SatO 2 at 5min,10min,15min and 20min after first full doses were obviously lower in groupⅠ than that in groupⅡ(P0 05).No severe adverse event was found during the observation.Conclusions Interference of epidural anesthesia with 0 375% ropivacaine on hemodynamics in breast cancer radical operation is slighter than that of 0 375% bupivacaine.