Effects of Leukocyte in the Injured Areas on Brain Edema After Brain Contusion in Rats
- VernacularTitle:脑挫裂伤时伤灶中的白细胞对脑水肿的影响
- Author:
Linxin XU
;
Yunsheng LIU
;
Dan JI
- Publication Type:Journal Article
- Keywords:
Brain injury;
Intracerebral hematoma;
Leukocyte;
Brain edema;
Leukocyte;
Animal experiment;
Rat
- From:
Journal of Chinese Physician
2000;0(12):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the effects of leukocyte in the injured foci on brain edema after brain contusion,in order to provide theoretical basis of clincial treatment of traumatic brain injury.Methods Traumatic brain injured animal model was established with injecton of blood components,forty five rats were randomly divided into three groups i.e,traumatic brain injure (TBI) group,whole blood(WB)group and white blood cell(WBC) group.Each group was further divided into three subgroups.All rats were killed at 24, 72 or 120 hours after injury,the water content, sodium, potassium and calcium contents were measured in brain tissue of areas injured.Results There was a peak of brain water and sodium contents in TBI, WB and WBC groups at 3 days after injury;Brain water content of TBI group was significantly lower than both WB group and WBC group (P
