Effect of Xinmailing Solution on neuronal cell injury induced by glutamate
- VernacularTitle:心脉灵注射液对培养神经细胞谷氨酸损伤的影响
- Author:
Yuzhong ZHANG
;
Jin QIU
;
Qifu HUANG
;
Kelin LI
- Publication Type:Journal Article
- Keywords:
Glutamates;
Neurons;
Xinmailing Solution;
MK-801
- From:
Chinese Journal of Pathophysiology
2000;0(11):-
- CountryChina
- Language:Chinese
-
Abstract:
AIM: To detect the effects of Xinmailing Solution and MK-801 on injury of neuronal cell induced by glutamate. METHODS: Cultured neuronal cell injuried by glutamate was prepared and the content of malondialdehyde and nitrite in cell supernatant was measured. Morphology changes were also observed with discrepancy microscope at the same time. RESULTS: Xinmailing Solution and MK-801 attenuated cell injury induced by glutamate,and inhibited increase in malondialdehyde and nitrite in cell supernatant. CONCLUSION: Xinmailing Solution had a protective effect on neuronal cell at cell level.
